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Puyallup 253-770-4720
Aberdeen 360-533-4997
Montesano 360-249-3000
Shelton 360-426-5654
Spokane Arthur St. 509-927-3668
Spokane Monroe St. 509-326-5172
© 2009-10 STOP & JBR
Antabuse (Disulfiram) is a drug given to alcoholics that produces adverse effects such as nausea, vomiting, dizziness, flushing, and tachycardia if alcohol is consumed. The drug's effectiveness is largely due to it's role as a deterrent.
Under normal metabolism, alcohol is broken down in the liver by the enzyme alcohol dehydrogenase to acetaldehyde, which is then converted by the enzyme acetaldehyde dehydrogenase to the harmless acetic acid. Disulfiram blocks this reaction at the intermediate stage by blocking the enzyme acetaldehyde dehydrogenase. After alcohol intake under the influence of disulfiram, the concentration of acetaldehyde in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone.
As acetaldehyde is one of the major causes of the symptoms of a "hangover" this produces immediate and severe negative reaction to alcohol intake. Some 5-10 minutes after alcohol intake, the person may experience the effects of a severe hangover for a period of 30 minutes up to several hours.
Symptoms include flushing of the skin, accelerated heart rate, shortness of breath, nausea, and vomiting.
Under normal metabolism, alcohol is broken down in the liver by the enzyme alcohol dehydrogenase to acetaldehyde, which is then converted by the enzyme acetaldehyde dehydrogenase to the harmless acetic acid. Disulfiram blocks this reaction at the intermediate stage by blocking the enzyme acetaldehyde dehydrogenase. After alcohol intake under the influence of disulfiram, the concentration of acetaldehyde in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone.
As acetaldehyde is one of the major causes of the symptoms of a "hangover" this produces immediate and severe negative reaction to alcohol intake. Some 5-10 minutes after alcohol intake, the person may experience the effects of a severe hangover for a period of 30 minutes up to several hours.
Symptoms include flushing of the skin, accelerated heart rate, shortness of breath, nausea, and vomiting.
Our staff will watch you consume your antabuse and verify the time and date you consumed your dose. Antabuse (disulfuram) is an alcohol antagonist and can only be consumed pursuant to a doctor's prescription. If you are in need of antabuse monitoring please contact a local STOP office today.
What is Antabuse?
What is Antabuse?